ForumIAS LATEST
- 04 June | MGP Strategy Series | GS Paper 4 (Ethics) with AIR 7 A.R. Rajah Mohaideen Click Here to register for the session →
- 04 June | GS Advance Program begins from 4th June 2026 | First 2 classes open to all Click Here to register for the event →
- 05 June | MGP Strategy Series | GS Paper 3 Strategy Session with AIR 406 Mannat Luthra Click Here to register for the session
- 06 June | Open Orientation on Essay Guidance Program (EGP 2026) Click Here to register →
- 07 June | Open Orientation for Current Affairs for Mains 2026 Click Here to register →
- 07 June | Sociology Optional Strategy Session with AIR 10 Ujjwal Priyank Click Here to register →
Contents
What is the News?
Indian researchers have developed a non-invasive, easy to administer, cost-effective, and patient compliant potential therapeutic strategy against Visceral Leishmaniasis.
About Leishmaniasis:
- The leishmaniases are a group of diseases caused by protozoan parasites. These parasites are transmitted to humans by the bite of an infected female phlebotomine sandfly, a tiny – 2–3 mm long – insect vector.
- Types: There are three main forms of this disease:
- Cutaneous leishmaniasis (CL)
- Visceral leishmaniasis (VL), also known as kala-azar, and
- Mucocutaneous leishmaniasis (MCL)
- CL is the most common form, VL is the most severe form and MCL is the most disabling form of the disease.
About Visceral Leishmaniasis(VL):
- Visceral Leishmaniasis(VL) is also known as kala-azar. The disease is characterized by irregular bouts of fever, substantial weight loss, swelling of the spleen and liver, and anaemia.
- It is a neglected tropical disease that affects millions annually, making it the second most common parasitic killer after malaria.
- If the disease is not treated, the fatality rate in developing countries can be as high as 100% within 2 years.
Treatment of VL:
- The conventional treatment therapy of VL mainly involves painful intravenous administration. This imposes many treatment complications, including prolonged hospitalization, high cost, and high risk of infection.
- On the other hand, Oral drug delivery brings forth massive advantages that can help overcome these barriers. But with oral routes have potential high renal toxic side effects.
- To overcome this, scientists have developed a method based on nano carrier-based oral drugs coated with Vitamin B12. This method can mitigate challenges and drug-associated toxicity.
